Understanding MCP, A2A, and CUA

AI is evolving beyond single copilots. Discover how Model Context Protocol (MCP), Agent-to-Agent (A2A) communication, and Computer Use Agents (CUA) are transforming how intelligent systems connect, collaborate, and act, redefining the future of automation.

Copilot Studio

Written by

Ankita Kajal

Published on

October 21, 2025
Understanding MCP (Model Context Protocol), A2A (Agent-to-agent) and CUA (Computer Use Agents) Protocols

Artificial Intelligence is entering a new era, one where systems no longer work in isolation but collaborate intelligently. This transformation is powered by three emerging protocols: Model Context Protocol (MCP), Agent-to-Agent (A2A) communication, and Computer Use Agents (CUA).

If your business is exploring how to scale AI or integrate Microsoft Copilot Studio into existing workflows, understanding these technologies will give you a head start.

What Are AI Agents?

AI agents are digital assistants that use intelligence to perform tasks, make decisions, and automate workflows. From answering customer questions to analysing financial data, these agents act on your behalf, individually or as a network. Microsoft’s Copilot Studio empowers organisations to create and manage these agents with ease.

But as companies develop more specialised agents, the real challenge is coordination, enabling agents to talk, share data, and collaborate securely. That’s where MCP, A2A, and CUA come into play.

Model Context Protocol (MCP): Connecting AI to Knowledge and Tools

The Model Context Protocol (MCP) acts as the bridge between large language models and enterprise data.

Think of it as a standardised interface that helps AI systems understand and use business information safely and efficiently.

The image shows the core components of MCP (Modern Context Protocol in Copilot Studio

Key Features

  • Unified access: Connects AI models directly to tools, APIs, and data sources. 
  • Standardised communication: Makes “function calling” consistent across platforms like Azure, OpenAI, and Anthropic. 
  • Context awareness: Keeps models updated with the latest company data. 
  • Secure integration: Reduces the risk of fragmented or ungoverned AI access. 

Why It Matters?

MCP enables AI systems to do more than generate text – they can act within context.

For instance, a Copilot built with MCP can automatically fetch CRM data, update sales records, or trigger workflows in Power Automate.

Agent-to-Agent (A2A): Enabling AI Collaboration

If MCP is how AI connects with systems, A2A is how AI agents connect. It’s a protocol that enables agents to communicate, share insights, and collaborate on complex tasks while maintaining their independence.

The image shows the working mechanism of A2A (Agent-to-agent) in Copilot Studio

How A2A Works?

  • Uses Agent Cards to identify capabilities. 
  • Shares multi-modal information – text, data, visuals, even audio. 
  • Enables secure negotiation and task sharing.
  • Ensures authentication and authorisation for every interaction

Business Impact

A2A allows businesses to move from isolated bots to collaborative ecosystems. Imagine a finance agent that alerts a project tracker agent about overspending, which then signals a reporting agent to generate insights – all autonomously.

At Synapx, we design multi-agent architectures that leverage A2A to connect Copilot Studio agents with enterprise data, driving faster, smarter decisions across departments.

Computer Use Agents (CUA): Letting AI See and Act

Computer Use Agents (CUA) take automation a step further by giving AI the ability to interact with screens just like humans do. They use vision and reasoning to navigate web apps, fill forms, and complete tasks that previously required manual input.

The image shows the detailed working of CUA (Computer Use Agents)

Core Capabilities

  • Understand visual layouts on desktop or web applications.
  • Automate data entry, reporting, or reconciliation across multiple systems.
  • Adapt dynamically when UI layouts change.
  • Combine multimodal inputs (text, vision, clicks) for full-spectrum automation.

Example

A CUA can log in to a supplier portal, download invoices, extract line-items into Excel, and send summaries to a manager – no coding, no human effort.

The Power of Multi-Agent Orchestration

When used together, MCP, A2A, and CUA form the foundation of next-generation intelligent automation:

ProtocolPurposeExample Use Case
MCPConnects AI models with structured data and toolsA Copilot retrieving live ERP data
A2AEnables communication between agentsFinance and HR agents collaborating on budget forecasting
CUAAllows AI to interact visually with appsAI agent processing invoices from a website

These layers allow your digital workforce to see, think, and act, creating a fully connected AI ecosystem.

How Synapx Can Help?

At Synapx, we help businesses build and integrate Copilot Studio agents using MCP, A2A, and CUA. Our team ensures your agents communicate securely, automate intelligently, and align perfectly with your business processes. Whether you’re starting your first AI agent project or orchestrating multi-agent workflows, Synapx delivers the expertise and governance your enterprise needs.

Conclusion

AI is no longer just about automation – it’s about collaboration between intelligent systems. Protocols like MCP, A2A, and CUA are redefining how organisations build, scale, and manage AI.

Businesses that embrace this shift will see not only operational efficiency but also entirely new ways of delivering value.

Frequently Asked Questions

These three protocols complement one another. MCP connects AI models to structured data and tools, A2A enables communication between multiple AI agents, and CUA allows those agents to interact visually with applications. Together, they form a seamless automation network where data flows intelligently, and tasks are executed without human intervention.

Yes. MCP, A2A, and CUA can be integrated into existing Copilot Studio environments. They expand the capabilities of your Copilots, allowing them to access enterprise data, collaborate with other agents, and even complete visual tasks across apps.

Absolutely. MCP and A2A both incorporate authentication, authorisation, and encryption layers to ensure secure data exchange. Synapx follows Microsoft’s best practices and governance models to maintain compliance and protect sensitive business information.

While every business can leverage intelligent agents, industries such as finance, insurance, IT services, and construction gain exceptional value, especially in areas like reporting automation, data reconciliation, and cross-departmental workflows.

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